Presenilin 1 (349-361)

• UNSPSC Description:

  Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the research of various diseases[1].

• Target Antigen:

  GSK-3

• Type:

  Peptides

• Related Pathways:

  PI3K/Akt/mTOR;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/presenilin-1-349-361.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1[C@@H](CCC1)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N3[C@@H](CCC3)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

• Molecular Weight:

  1364.47

• References & Citations:

  [1]Kai Prager, et al. A structural switch of presenilin 1 by glycogen synthase kinase 3beta-mediated phosphorylation regulates the interaction with beta-catenin and its nuclear signaling. J Biol Chem. 2007 May 11;282(19):14083-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  956004-39-0