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(-) -Corynoxidine

CAT: 0804-HY-N7010Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7010Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Corynoxidine is an acetylcholinesterase inhibitor with an IC50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa[1]. (-) -Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees[2].
CAS Number
57906-85-1
UNSPSC
12352005
Target
Bacterial; Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Anti-infection; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/corynoxidine.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=CC=C2C(C[N@@+]3([O-])CCC4=CC(OC)=C(OC)C=C4[C@]3([H])C2)=C1OC
Molecular Formula
C21H25NO5
Molecular Weight
371.43
References & Citations
[1]Kim DK, et al. Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch Pharm Res. 2004 Nov;27 (11) :1127-31.|[2]Yang DL, et al. A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera. J Asian Nat Prod Res. 2013;15 (3) :315-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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