Lycorine (hydrochloride) (Standard)

Lycorine (hydrochloride) (Standard)

• CAS Number: 2188-68-3
• UNSPSC Description: Lycorine (hydrochloride) (Standard) is the analytical standard of Lycorine (hydrochloride). This product is intended for research and analytical applications. Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (L’Her.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity[1]. Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells (IC50 of 1.2 μM)[2].
• Target Antigen: Autophagy; Bacterial; Virus Protease
• Type: Reference Standards
• Related Pathways: Anti-infection;Autophagy
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/lycorine-hydrochloride-standard.html
• Smiles: O[C@@H]1[C@@H](O)C=C(CC2)[C@@]3([H])N2CC4=C([C@@]31[H])C=C(OCO5)C5=C4.Cl
• Molecular Weight: 323.77
• References & Citations: [1]Liu, R. et al. Lycorine hydrochloride inhibits metastatic melanoma cell-dominant vasculogenic mimicry. Pigment cell & melanoma research 25, 630-638, doi:10.1111/j.1755-148X.2012.01036.x (2012).|[2]Cao, Z. et al.Lycorine hydrochloride selectively inhibits human ovarian cancer cell proliferation and tumor neovascularization with very low toxicity. Toxicology letters 218, 174-185, doi:10.1016/j.toxlet.2013.01.018 (2013).
• Shipping Conditions: Room temperature