6-Thioguanosine

• UNSPSC Description:

  6-Thioguanosine (6-Mercaptoguanosine), an active nucleoside, is an Azathioprine metabolite. 6-Thioguanosine has immunosuppressive effects[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/6-thioguanosine.html

• Purity:

  98.23

• Solubility:

  DMSO : 20 mg/mL (ultrasonic)

• Smiles:

  NC1=NC(C2=C(N1)N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=S

• Molecular Weight:

  299.312

• References & Citations:

  [1]Amedeo De Nicolò, et al. UPLC-MS/MS method for quantification of the azathioprine metabolites 6-mercaptoguanosine and 6-methylmercaptopurine riboside in peripheral blood mononuclear cells. J Pharm Biomed Anal. 2014 Sep;98:271-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  85-31-4