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Thymidine-13C-2

CAT: 0804-HY-N1150S4-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1150S4-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thymidine-13C-2 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
Product Name Alternative
DThyd-13C-2; NSC 21548-13C-2
UNSPSC
12352005
Target
DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Orthopoxvirus
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thymidine-13c-2.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H](C[13C@H](N2C(NC(C(C)=C2)=O)=O)O1)O
Molecular Formula
C9 13CH14N2O5
Molecular Weight
243.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8 (17) .; FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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