Puxitatug samrotecan drug-linker

• UNSPSC Description:

  Puxitatug samrotecan drug-linker (AZD8205 drug-linker) is part of the anti-B7-H4 antibody-conjugated active molecule ADC (drug-linker conjugate for ADC). Puxitatug samrotecan drug-linker contains a degradable ADC linker and a topoisomerase I inhibitor Exatecan (HY-13631)[1].

• Target Antigen:

  Drug-Linker Conjugates for ADC

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/puxitatug-samrotecan-drug-linker.html

• Smiles:

  O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(C(CC6=O)SC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=CC7=C1COC([C@]7(O)CC)=O

• Molecular Weight:

  1269.42

• References & Citations:

  [1]Conilh L, et al. Payload diversification: a key step in the development of antibody–drug conjugates[J]. Journal of Hematology & Oncology, 2023, 16(1): 3.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3025787-81-6