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NTCP2 rabbit pAb

CAT: 0855-ES14442-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14442-01Size:50 µL
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Background
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM) ; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG) . [provided by RefSeq, Mar 2010]
Description
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010],
UniProt
Q12908
Swiss Prot
Q12908
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human NTCP2 AA range: 46-96
Target
NTCP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Gene ID (Human)
6555

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MBS6009712-01SLC10A2, CT (SLC10A2, ASBT, ISBT, NTCP2, Ileal sodium/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, ileal, Solute carrier family 10 member 2)
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