Anti-ABCG2 [5D3]

• Gene Name:

  [ABCG2]

• NCBI Gene ID:

  9429

• Reactivity:

  Human

• Storage Conditions:

  Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

• Specificity:

  This antibody recognizes and binds a conformation-sensitive external epitope of ABCG2 on living cells. ABCG2 is a broad substrate specificity ATP-dependent transporter from the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. (PMID:11306452, 12958161, 19506252, 20705604, 28554189, 30405239, 31003562). The human ABCG2 protein is an important primary active transporter for hydrophobic compounds in several cell types, and its overexpression causes multidrug resistance in tumors (PMID: 15557326). ABCG2 is associated with drug resistance in acute myeloid leukemia (AML) (PMID: 12393637). ABCG2 expression may also have potential as a marker that identifies human limbal epithelial stem cells (PMID: 15625123).

• Other Gene Names:

  [ABCG2; ABCG2; MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; CDw338; UAQTL1; EST157481; ABCP; BCRP; BCRP1; MXR]

• Short Name:

  [ABCG2]

• Other Product Names:

  [ATP-binding cassette sub-family G member 2; ATP-binding cassette sub-family G member 2; ATP-binding cassette sub-family G member 2; urate exporter; ABC transporter; placenta specific MDR protein; breast cancer resistance protein; ATP-binding cassette transporter G2; mitoxantrone resistance-associated protein; placenta-specific ATP-binding ca; ATP-binding cassette, sub-family G (WHITE), member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporter]

• NCBI GI Number:

  67462103

• NCBI Accession Number:

  Q9UNQ0.3

• Uniprot Accession Number:

  Q9UNQ0