Products for Research Use Only
RegisterLogin

Ursodeoxycholic acid (Standard)

CAT: 0804-HY-13771R-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-13771R-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno) deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR) . Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active[1][2][3][4].
CAS Number
128-13-2
Product Name Alternative
Ursodeoxycholate (Standard) ; Ursodiol (Standard) ; UDCA (Standard)
UNSPSC
12352211
Target
Angiotensin-converting Enzyme (ACE) ; Endogenous Metabolite; FXR; G protein-coupled Bile Acid Receptor 1; Reference Standards
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ursodeoxycholic-acid-standard.html
Purity
99.83
Smiles
C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Formula
C24H40O4
Molecular Weight
392.57
References & Citations
[1]Jackson H, et al. Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study. Hepatology. 2007 Oct;46 (4) :1131-7.|[2]Kumar D, et al. Use of ursodeoxycholic acid in liver diseases. J Gastroenterol Hepatol. 2001 Jan;16 (1) :3-14.|[3]Biao Nie, et al. Specific Bile Acids Inhibit Hepatic Fatty Acid Uptake in Mice. Hepatology. 2012 Oct;56 (4) :1300-10.|[4]Brevini T, et al. FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature. 2022 Dec 5.|[5]Winston JA, et al. Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice. PLoS One. 2021;16 (2) :e0246161. Published 2021 Feb 18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-13771-01Ursodeoxycholic acid
HY-13771S1-01Ursodeoxycholic acid-13C
HY-113478-013β-Ursodeoxycholic acid
HY-13771A-01Ursodeoxycholic acid (sodium)
HY-113478S-01Ursodeoxycholic acid-d4
HY-W752912Tauro-d4-ursodeoxycholic acid
HY-W6998133β-Ursodeoxycholic acid-d5
HY-149754Ursodeoxycholic acid 7-N-acetylglucosaminide
HY-132686S-01Ursodeoxycholic acid methyl ester-d5
HY-W75994724-Nor ursodeoxycholic acid-d5 acyl-b-D-glucuronide

Alternative Products

CatalogName
TBZ2838Ursodeoxycholic acid
FU28646-013beta-Ursodeoxycholic acid
MBS3616513-01Ursodeoxycholic acid sodium
TRC-U850007-1MGUrsodeoxycholic Acid-d4

Popular Products