(R)-Propranolol (hydrochloride)

• UNSPSC Description:

  (R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology; Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/r-propranolol-hydrochloride.html

• Purity:

  99.36

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)|H2O : 7.14 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O[C@@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl

• Molecular Weight:

  295.80

• References & Citations:

  [1]A M Barrett,et al. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias. Br J Pharmacol

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  13071-11-9