8-Hydroxyquinoline (Standard)

8-Hydroxyquinoline (Standard)

• CAS Number: 148-24-3
• UNSPSC Description: 8-Hydroxyquinoline (Standard) is the analytical standard of 8-Hydroxyquinoline. This product is intended for research and analytical applications. 8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice[1][2][3][4][5].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference Standards
• Related Pathways: Anti-infection
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/8-hydroxyquinoline-standard.html
• Smiles: OC1=C2N=CC=CC2=CC=C1
• Molecular Weight: 145.16
• References & Citations: [1]Lawung R, et.al. Repositioning of 8-hydroxyquinoline derivatives as a new promising candidate for combating multidrug resistant Neisseria gonorrhoeae. EXCLI J. 2018 Aug 23;17:840-846. |[2]8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells. J Biol Inorg Chem. 2010 Feb;15(2):259-69. |[3]Zhai S, et.al. Tumor cellular proteasome inhibition and growth suppression by |[4]Hamoud MA, et.al. Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay. Teratog Carcinog Mutagen. 1989;9(2):111-8. |[5]Searle CE. The selective depigmenting action of 8-hydroxyquinoline on hair growth in the mouse. Br J Dermatol. 1972 May;86(5):472-80.
• Shipping Conditions: Room temperature