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VU 0238429

CAT: 0804-HY-12157-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12157-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5), with an EC50 of 1.16 μM.
CAS Number
1160247-92-6
UNSPSC
12352005
Hazard Statement
H319, H400
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/VU_0238429.html
Purity
99.96
Solubility
DMSO : ≥ 150 mg/mL
Smiles
O=C1N(CC2=CC=C(OC)C=C2)C3=C(C=C(OC(F)(F)F)C=C3)C1=O
Molecular Formula
C17H12F3NO4
Molecular Weight
351.28
Precautions
H319, H400
References & Citations
[1]Bridges TM, et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR5

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