VU 0360223

• Description :

  VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].

• UNSPSC :

  12352005

• Target :

  MGluR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/vu-0360223.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N#CC1=CC(C2=CC=C(SC(C)=N3)C3=C2)=CC(F)=C1

• Molecular Formula :

  C15H9FN2S

• Molecular Weight :

  268.31

• References & Citations :

  [1]Pomierny-Chamioło L, et al. Metabotropic glutamatergic receptors and their ligands in drug addiction. Pharmacol Ther. 2014 Jun;142 (3) :281-305.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MGluR

• CAS Number :

  [1274859-33-4]