Corticosterone (Standard)

Corticosterone (Standard)

• CAS Number: 50-22-6
• UNSPSC Description: Corticosterone (Standard) is the analytical standard of Corticosterone. This product is intended for research and analytical applications. Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect[1][2][3][4].
• Target Antigen: Endogenous Metabolite; Glucocorticoid Receptor; iGluR
• Type: Reference Standards
• Related Pathways: Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Vitamin D Related/Nuclear Receptor
• Field of Research: Endocrinology; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/corticosterone-standard.html
• Smiles: C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
• Molecular Weight: 346.46
• Shipping Conditions: Room temperature
• Clinical Information: Phase 3