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Levamlodipine

CAT: 0804-HY-14744-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14744-01Size:5 mg
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Description
Levamlodipine ((S) -Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].
CAS Number
[103129-82-4]
Product Name Alternative
(S) -Amlodipine; Levoamlodipine
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Calcium Channel; SOD
Type
Reference compound
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/levamlodipine.html
Purity
98.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC
Molecular Formula
C20H25ClN2O5
Molecular Weight
408.88
Precautions
H315, H319, H320
References & Citations
[1]Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.|[2]Rong H, et al. [Effect of probucol on serum malondialdehyde and superoxide dismutase in patients with primary hypertension]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 May;37 (5) :458-62.|[3]Yang YL, et al. Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats. CNS Neurosci Ther. 2012 Jun;18 (6) :471-4.|[4]Lee YJ, et al. Amlodipine besylate and amlodipine camsylate prevent cortical neuronal cell death induced by oxidative stress. J Neurochem. 2011 Dec;119 (6) :1262-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Proc Natl Acad Sci U S A. 2025 May 6;122 (18) :e2425494122.|Cell. 2023 Nov 22;186 (24) :5363-5374.e16.

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