ULK-101
CAT:
804-HY-114490-02
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ULK-101
- CAS Number: 2443816-45-1
- UNSPSC Description: ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress[1].
- Target Antigen: ULK
- Type: Reference compound
- Related Pathways: Autophagy
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ULK-101.html
- Purity: 99.96
- Solubility: DMSO : 83.33 mg/mL (ultrasonic)
- Smiles: FC1=CC=C(C(C=N2)=CN3C2=C(C4=CSC(C(N[C@@H](C5CC5)C(F)(F)F)=O)=C4)C=N3)C=C1
- Molecular Weight: 460.45
- References & Citations: [1]Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported