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S 39625

CAT: 0804-HY-122014Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122014Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
39625 is a camptothecin ketone analogue, a stable, potent and selective topoisomerase I inhibitor, active against purified topoisomerase I and cytotoxic to cancer cells.
CAS Number
536711-20-3
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-39625.html
Smiles
O=C1C2=C(C(C(C2)=O)(CC)O)C=C3C4=C(CN13)C(C5CCC5)=C6C=C7OCOC7=CC6=N4
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
References & Citations
[1]Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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