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1-Thioglycerol

CAT: 0804-HY-W010572-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W010572-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.
CAS Number
96-27-5
Product Name Alternative
Alpha-Thioglycerol
UNSPSC
12352200
Hazard Statement
H302, H311+H331, H315, H317, H402
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-thioglycerol.html
Purity
99.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
SCC(CO)O
Molecular Formula
C3H8O2S
Molecular Weight
108.16
Precautions
H302, H311+H331, H315, H317, H402
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Chemical Information

Thioglycerol

Monothioglycerol is a thiol that is glycerol in which one of the primary hydroxy groups is replaced by a thiol group. It has a role as a reducing agent and a vulnerary. It is a member of propane-1,2-diols and a thiol.

CAS Number96-27-5
PubChem CID7291
IUPAC Name3-sulfanylpropane-1,2-diol
Molecular FormulaC3H8O2S
Molecular Weight108.16
XLogP-0.8
Topological Polar Surface Area41.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count6
Formal Charge0
Complexity32
SMILES
C(C(CS)O)O
InChI
InChI=1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2
InChIKey
PJUIMOJAAPLTRJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Thioglycerol
CAS: 96-27-5
CID: 7291
Formula: C3H8O2S
MW: 108.16
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight108.16
XLogP3-0.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass108.02450067
Monoisotopic Mass108.02450067
Topological Polar Surface Area41.5 Ų
Heavy Atom Count6
Formal Charge0
Complexity32
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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