β-catenin-IN-3
CAT:
804-HY-147007-03
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

β-catenin-IN-3
- CAS Number: 1005288-15-2
- UNSPSC Description: β-catenin-IN-3 (compound C2) is a potent and selective β-catenin inhibitor with a KD value of 54.96 nM. β-catenin-IN-3 acts by targeting a cryptic allosteric modulation site of β-catenin. β-catenin-IN-3 can significantly reduce viability of β-catenin-driven cancer cells[1].
- Target Antigen: Wnt; β-catenin
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/β-catenin-in-3.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: S=C(N/C=C/C(C=C1Br)=C(C(Br)=C1)O)NC(C2)C3C(C=CC4)C4C2C3
- Molecular Weight: 484.25
- References & Citations: [1]Cheltsov A, et al. Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer. Sci Rep. 2020;10(1):8096. Published 2020 May 15.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported