HC-Toxin
CAT:
804-HY-126856-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HC-Toxin
- CAS Number: 83209-65-8
- UNSPSC Description: HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC50 of 30 nM[1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects[2].
- Target Antigen: Apoptosis; HDAC
- Type: Natural Products
- Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Epigenetics
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hc-toxin.html
- Purity: 99.26
- Solubility: 10 mM in DMSO
- Smiles: O=C([C@@H](NC([C@H]1C)=O)CCCCCC([C@@H]2CO2)=O)N3[C@](C(N[C@H](C(N1)=O)C)=O)([H])CCC3
- Molecular Weight: 436.50
- References & Citations: [1]S J Darkin-Rattray, et al. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13143-7.|[2]Ki Eun Joung, et al. Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. Arch Pharm Res. 2004 Jun;27(6):640-5.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light)
- Clinical Information: No Development Reported