Human HDAC2 (recombinant)

Human HDAC2 (recombinant)_x000D_ Catalog number: B2016773_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 56.1 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Histone Deacetylase 2_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Mao QD, Zhang W, Zhao K, Cao B, Yuan H, Wei LZ, Song MQ, Liu XS. MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer Braz J Med Biol Res. 2017 May 18;50(6):e6103._x000D_ 2: Zhang H, Zhao B, Huang C, Meng XM, Bian EB, Li J. Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells PLoS One. 2014 May 2;9(5):e95520._x000D_ 3: Kim JK, Noh JH, Eun JW, Jung KH, Bae HJ, Shen Q, Kim MG, Chang YG, Kim SJ, Park WS, Lee JY, Borlak J, Nam SW. Targeted inactivation of HDAC2 restores p16INK4a activity and exerts antitumor effects on human gastric cancer Mol Cancer Res. 2013 Jan;11(1):62-73._x000D_ 4: Kim HS, Chang YG, Bae HJ, Eun JW, Shen Q, Park SJ, Shin WC, Lee EK, Park S, Ahn YM, Park WS, Lee JY, Nam SW. Oncogenic potential of CK2α and its regulatory role in EGF-induced HDAC2 expression in human liver cancer FEBS J. 2014 Feb;281(3):851-61._x000D_ 5: La Noce M, Paino F, Mele L, Papaccio G, Regad T, Lombardi A, Papaccio F, Desiderio V, Tirino V. HDAC2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy J Exp Clin Cancer Res. 2018 Dec 3;37(1):296._x000D_ 6: Li J, Staver MJ, Curtin ML, Holms JH, Frey RR, Edalji R, Smith R, Michaelides MR, Davidsen SK, Glaser KB. Expression and functional characterization of recombinant human HDAC1 and HDAC3 Life Sci. 2004 Apr 16;74(22):2693-705._x000D_ 7: Fumet JD, Limagne E, Thibaudin M, Truntzer C, Bertaut A, Rederstorff E, Ghiringhelli F. Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment BMC Cancer. 2020 Aug 10;20(1):748._x000D_ 8: Adams MK, Banks CAS, Miah S, Killer M, Washburn MP. Purification and enzymatic assay of class I histone deacetylase enzymes Methods Enzymol. 2019;626:23-40._x000D_ 9: Pandey D, Sikka G, Bergman Y, Kim JH, Ryoo S, Romer L, Berkowitz D. Transcriptional regulation of endothelial arginase 2 by histone deacetylase 2 Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1556-1566._x000D_ 10: Song H, Tao L, Chen C, Pan L, Hao J, Ni Y, Li D, Li B, Shi G. USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation Int J Clin Exp Pathol. 2015 Sep 1;8(9):10707-15. eCollection 2015._x000D_ _x000D_ Products Related to Human HDAC2 (recombinant) can be found at Proteins

9000-83-3

Catalog Number: B2016773 (50 µg)

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