Sheep anti Human Rhombotin 2

Sheep anti Human Rhombotin 2

• Background: Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on Human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur; all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved.
• Synonyms: LIM Domain only Protein, cysteine-rich Protein TTG-2, T-Cell translocation Protein 2
• UniProt: P25791 (Human)
• Host: Sheep
• Species Reactivity: Human
• Isotype: IgG
• Conjugation: Unconjugated
• Type: Polyclonal Antibody
• Applications: WB
• Field of Research: Inflammation and Immunology
• Purification Method: Ammonium Sulfate Precipitation
• Assay Principle: Western Blots at 1-10 µg /mL
• Stability: See expiration date on vial
• Concentration: See vial for Concentration
• Form: Provided as solution in phosphate buffered saline with 0,08% sodium azide
• Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
• Shipping Conditions: Room Temperature
• Storage Conditions: Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
• Functional Analysis: WB