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P11

CAT: 0804-HY-111053-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111053-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P11 is a selective inhibitor of platelet-activating factor acetylhydrolases (PAFAHs) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC50 values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively[1].
CAS Number
942285-55-4
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p11.html
Purity
99.69
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(N1[C@](C2=CC=C(C=C2)C(C)(C)C)([H])C(C(O)=O)=CC[C@@]1([H])C3=CC=C(C=C3)C)(C4=CC=C(C=C4)C)=O
Molecular Formula
C30H33NO4S
Molecular Weight
503.65
References & Citations
[1]Jae Won Chang, et al. Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. ACS Chem Biol. 2015 Apr 17;10 (4) :925-32.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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