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ASCC3 rabbit pAb

CAT: 0855-ES18234-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES18234-01Size:50 µL
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Background
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Description
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
UniProt
Q8N3C0
Swiss Prot
Q8N3C0
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human ASCC3 AA range: 2053-2103
Target
ASCC3
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Nucleus speckle . Cytoplasm, cytosol . Colocalizes with ALKBH3 and ASCC2 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. .
Gene ID (Human)
10973

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