MS-0022

• UNSPSC Description:

  MS-0022 is a Smoothened (SMO) antagonist. MS-0022 can inhibit the Hedgehog (Hh) signaling pathway. MS-0022 can be used in anti-tumor research[1].

• Target Antigen:

  Hedgehog; Smo

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ms-0022.html

• Smiles:

  O=C(NC1=CC=C(C2=CN3C=CC=C(C)C3=N2)C=C1)C4=CC=CC=C4Br

• Molecular Weight:

  406.28

• References & Citations:

  [1]Strand MF, et al. A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model. PLoS One. 2011;6(6):e19904.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  691392-89-9