10074-A4

• Description :

  10074-A4 is a c-Myc inhibitor. 10074-A4 could bind to c-Myc370-409 at different sites along the peptide chain. 10074-A4 has anticancer effects[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  C-Myc

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/10074-a4.html

• Purity :

  98.22

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(SCC1=O)N1CC(CN2C3=C(C=C(C=C3)Cl)C4=C2C=CC(Cl)=C4)O

• Molecular Formula :

  C18H14Cl2N2O3S

• Molecular Weight :

  409.29

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Chen Yu, et al. Structure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc. Sci Rep. 2016 Mar 2;6:22298.|[2]Fan Jin, et al. Ligand clouds around protein clouds: a scenario of ligand binding with intrinsically disordered proteins. PLoS Comput Biol. 2013;9 (10) :e1003249.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [312631-87-1]