Products for Research Use Only
RegisterLogin

Sclerostin/SOST

CAT: 0426-E21-D48Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0426-E21-D48Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Description
Recombinant Human Sclerostin is produced by our Mammalian expression system and the target gene encoding Gln24-Tyr213 is expressed with a 6His tag at the C-terminus.
Synonyms
Sclerostin; SOST; UNQ2976; PRO7455; PRO7476
Expression System
Human cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 250mM NaCl, pH 8.0.
Species
Human
Shipping Temperature
Ambient

Related Products

CatalogName
E42EH-54Human SOST/Sclerostin ELISA KIT
E42EH-54-48THuman SOST/Sclerostin ELISA KIT
E42EH-54-96THuman SOST/Sclerostin ELISA KIT
E45K00437Rat Sost/Sclerostin ELISA Kit
E24CHA635Anti-SOST / Sclerostin Reference Antibody (blosozumab)
E24CHA334Anti-SOST / Sclerostin Reference Antibody (setrusumab)
E24CHA335Anti-SOST / Sclerostin Reference Antibody (romosozumab)
E51P01825SOST/Sclerostin Protein, Mouse, Recombinant (N-His)
E45R53756M2-20SOST/Sclerostin Protein, Rat, Recombinant (His Tag)
E40KMP1302Recombinant human SOST/Sclerostin Protein, His Tag

Alternative Products

CatalogName
216961SOST (Sclerostin)
PX-P4621-100Sclerostin (SOST)
MBS8532942-01Sclerostin/SOST
042146SOST, ID (SOST, Sclerostin)
MBS643793-01SOST, NT (SOST, Sclerostin)
MBS6349873-01SOST, NT (SOST, Sclerostin) (FITC)
MBS6349871-01SOST, NT (SOST, Sclerostin) (APC)
MBS6349858-01SOST, ID (SOST, Sclerostin) (PE)
SIPC477Mu01-01Recombinant Sclerostin (SOST)
abx321641-01Sclerostin (SOST) Antibody

Popular Products