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GSK3A antibody

CAT: 0710-FNab10243Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10243Size:100 µg
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Background
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
Synonyms
Glycogen synthase kinase-3 alpha (GSK-3 alpha) |Serine/threonine-protein kinase GSK3A|GSK3A
Gene ID
2931
UniProt
P49840
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Glycogen synthase kinase 3 alpha
Target
GSK3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
51 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
Peptide

UniProtKB · P49840

Glycogen synthase kinase-3 alpha

GSK3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49840
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSK3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GSK-3 alpha
EC number
2.7.11.26
Processing
—
Secondary accessions
O14959
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Disease

Alzheimer diseaseDiabetes mellitus

Ligand

ATP-bindingNucleotide-binding

Biological process

Carbohydrate metabolismGlycogen metabolismNeurogenesisWnt signaling pathway

Molecular function

KinaseSerine/threonine-protein kinaseSignal transduction inhibitorTransferase

Alternative Products