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PTCH1 antibody

CAT: 0710-FNab10084Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10084Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH) . Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Synonyms
Protein patched homolog 1 (PTC, PTC1) |PTCH1|PTCH
Gene ID
5727
UniProt
Q13635
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Patched homolog 1
Target
PTCH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Neuroscience, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
161 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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