Phospho-EIF2S1 (Ser51) antibody antibody

• Background:

  Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

• Synonyms:

  Eukaryotic translation initiation factor 2 subunit 1|Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2-alpha)|EIF2S1|EIF2A

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

• Target:

  Phospho-EIF2S1 (Ser51)

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Applications:

  ELISA, WB

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:1000-1:10000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4