Phospho-EIF2S1 (Ser51) antibody antibody

Phospho-EIF2S1 (Ser51) antibody antibody

• Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
• Synonyms: Eukaryotic translation initiation factor 2 subunit 1|Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2-alpha)|EIF2S1|EIF2A
• CAS Number: 9007-83-4
• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Immunogen: eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
• Target: Phospho-EIF2S1 (Ser51)
• Clonality: Monoclonal
• Isotype: IgG1
• Applications: ELISA, WB
• Purification: Protein A+G purification
• Dilution: WB: 1:1000-1:10000
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)