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ATP2A2 antibody

CAT: 0710-FNab09918Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09918Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of the SERCA Ca (2+) -ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2, SR Ca (2+) -ATPase 2) |Calcium pump 2|Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform|Endoplasmic reticulum class 1/2 Ca (2+) ATPase|ATP2A2|ATP2B
Gene ID
488
UniProt
P16615
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ATP2A2
Target
ATP2A2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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