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ATP6AP2 antibody

CAT: 0710-FNab07241Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07241Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the renin–angiotensin system (RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascular endothelial cells of the retina, in which it seems to be involved in pathological neovascularization processes. The present study demonstrates for the first time that the PRR is expressed in human ATP6AP2 and suggests a molecular mechanism by which hypertension may exacerbate the pathology of dry AMD.
Synonyms
Renin receptor|ATPase H (+) -transporting lysosomal accessory protein 2|ATPase H (+) -transporting lysosomal-interacting protein 2|ER-localized type I transmembrane adapter|Embryonic liver differentiation factor 10|N14F|Renin/prorenin receptor|Vacuolar ATP synthase membrane sector-associated protein M8-9 (ATP6M8-9, V-ATPase M8.9 subunit) |Renin receptor N-terminal fragment|Renin receptor C-terminal fragment|ATP6AP2|ATP6IP2|CAPER|ELDF10
Gene ID
10159
UniProt
O75787
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ATPase, H+ transporting, lysosomal accessory protein 2
Target
ATP6AP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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