ITGB2 antibody

• Background:

  This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

• Synonyms:

  Integrin beta-2|Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta|Complement receptor C3 subunit beta|ITGB2|CD18|MFI7

• Gene ID:

  3689

• UniProt:

  P05107

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  ITGB2

• Target:

  ITGB2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  85 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF