BIRC5 antibody

• Background:

  This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• Synonyms:

  Baculoviral IAP repeat-containing protein 5|Apoptosis inhibitor 4|Apoptosis inhibitor survivin|BIRC5|API4|IAP4

• Gene ID:

  332

• UniProt:

  O15392

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  SURVIVIN

• Target:

  BIRC5

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Applications:

  ELISA, WB

• Field of Research:

  Metabolism, Immunology, Cancer, Neuroscience, Cell Division and Proliferation

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:1000-1:6000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  18 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  4E7

• Tested Applications:

  ELISA, WB