BIRC2 antibody

• Background:

  BIRC2 (also known as cIAP1) is a member of the inhibitor of apoptosis protein (IAP) family. The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway (PMID: 15265700) . This cIAP1 antibody can bind both full length (70kd) and cleaved form (60kd) of the protein.

• Synonyms:

  Baculoviral IAP repeat-containing protein 2|Cellular inhibitor of apoptosis 1 (C-IAP1) |IAP homolog B|Inhibitor of apoptosis protein 2 (hIAP-2, hIAP2) |RING finger protein 48|RING-type E3 ubiquitin transferase BIRC2|TNFR2-TRAF-signaling complex protein 2|BIRC2|API1|MIHB|RNF48

• UniProt:

  Q13490

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Baculoviral IAP repeat-containing 2

• Target:

  BIRC2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  70 kDa, 60 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF