BIRC2 antibody

• Background :

  BIRC2 (also known as cIAP1) is a member of the inhibitor of apoptosis protein (IAP) family. The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway (PMID: 15265700) . This cIAP1 antibody can bind both full length (70kd) and cleaved form (60kd) of the protein.

• Synonyms :

  Baculoviral IAP repeat-containing protein 2|Cellular inhibitor of apoptosis 1 (C-IAP1) |IAP homolog B|Inhibitor of apoptosis protein 2 (hIAP-2, hIAP2) |RING finger protein 48|RING-type E3 ubiquitin transferase BIRC2|TNFR2-TRAF-signaling complex protein 2|BIRC2|API1|MIHB|RNF48

• UniProt :

  Q13490

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Baculoviral IAP repeat-containing 2

• Target :

  BIRC2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  70 kDa, 60 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF