ZC3H8 antibody
CAT:
710-FNab09605
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZC3H8 antibody
- Background: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region(IRR) of the GATA3 gene(By similarity). Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
- Synonyms: Zinc finger CCCH domain-containing protein 8|ZC3H8|ZC3HDC8
- CAS Number: 9007-83-4
- Gene ID: 84524
- UniProt: Q8N5P1
- Host: Rabbit
- Reactivity: Human
- Immunogen: zinc finger CCCH-type containing 8
- Target: ZC3H8
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB
- Field of Research: Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:1000-1:10000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 34 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)