ACTA2 antibody

• Background:

  The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• Synonyms:

  Actin, aortic smooth muscle|Alpha-actin-2|Cell growth-inhibiting gene 46 protein|Actin, aortic smooth muscle, intermediate form|ACTA2|ACTSA|ACTVS|alpha-Smooth Muscle Actin|α-SMA

• Gene ID:

  59

• UniProt:

  P62736

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Actin, alpha 2, smooth muscle, aorta

• Target:

  ACTA2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB

• Field of Research:

  Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience, Cell Division and Proliferation

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  42 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, WB