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WIPI1 antibody

CAT: 0710-FNab09512Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09512Size:100 µg
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Background
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.
Synonyms
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) |Atg18 protein homolog|WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa) |WIPI1|WIPI49
Gene ID
55062
UniProt
Q5MNZ9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
WD repeat domain, phosphoinositide interacting 1
Target
WIPI1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
46 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q5MNZ9

WD repeat domain phosphoinositide-interacting protein 1

WIPI1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5MNZ9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WIPI1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
WIPI-1
EC number
—
Processing
—
Secondary accessions
Q8IXM5, Q9NWF8
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Autophagy

Cellular component

CytoplasmCytoplasmic vesicleCytoskeletonEndosomeGolgi apparatusMembrane

Ligand

Lipid-binding

Technical term

Proteomics identificationReference proteome

Domain

RepeatWD repeat

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