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FLT4 antibody

CAT: 0710-FNab09394Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09394Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Synonyms
Vascular endothelial growth factor receptor 3 (VEGFR-3) |Fms-like tyrosine kinase 4 (FLT-4) |Tyrosine-protein kinase receptor FLT4|FLT4|VEGFR3
Gene ID
2324
UniProt
P35916
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fms-related tyrosine kinase 4
Target
FLT4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
152 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P35916

Vascular endothelial growth factor receptor 3

VGFR3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35916
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FLT4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VEGFR-3
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
A8K6L4, B5A926, Q16067, Q86W07, Q86W08
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Angiogenesis

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneNucleusSecreted

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

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