USP22 antibody

• Background :

  Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

• Synonyms :

  Ubiquitin carboxyl-terminal hydrolase 22|Deubiquitinating enzyme 22|Ubiquitin thioesterase 22|Ubiquitin-specific-processing protease 22|USP22|KIAA1063|USP3L

• Gene ID :

  23326

• UniProt :

  Q9UPT9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Ubiquitin specific peptidase 22

• Target :

  USP22

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Epigenetics, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:200-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  66 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB