TNNC1 antibody
CAT:
710-FNab08835
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TNNC1 antibody
- Background: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
- Synonyms: Troponin C, slow skeletal and cardiac muscles (TN-C)|TNNC1|TNNC
- CAS Number: 9007-83-4
- Gene ID: 7134
- UniProt: P63316
- Host: Rabbit
- Reactivity: Human, Mouse
- Immunogen: troponin C type 1 (slow)
- Target: TNNC1
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IHC, IF
- Field of Research: Neuroscience, Cardiovascular, Developmental biology, Signal Transduction
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 18 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)