ACTA2 antibody

• Background:

  ACTA2, also named as a-SMA, AAT6; ACTSA belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) . The immunogen of this antibody is a specific domain of ACTA2. This antibody stains the aorta only.

• Synonyms:

  Actin, aortic smooth muscle|Alpha-actin-2|Cell growth-inhibiting gene 46 protein|Actin, aortic smooth muscle, intermediate form|ACTA2|ACTSA|ACTVS|alpha-Smooth Muscle Actin|α-SMA

• Gene ID:

  59

• UniProt:

  P62736

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Actin, alpha 2, smooth muscle, aorta

• Target:

  ACTA2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB, IF

• Field of Research:

  Epigenetics, Cancer, Signal Transduction, Metabolism, Neuroscience

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  42 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, WB, IF

• Immunogen Sequence:

  Peptide