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TIMM22 antibody

CAT: 0710-FNab08699Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08699Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity) .
Synonyms
Mitochondrial import inner membrane translocase subunit Tim22|Testis-expressed protein 4|TIMM22|TEX4|TIM22
Gene ID
29928
UniProt
Q9Y584
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Translocase of inner mitochondrial membrane 22 homolog (yeast)
Target
TIMM22
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
20 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q9Y584

Mitochondrial import inner membrane translocase subunit Tim22

TIM22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y584
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TIMM22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9NWI8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variantPrimary mitochondrial disease

PTM

Disulfide bond

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Biological process

Protein transportTranslocationTransport

Domain

TransmembraneTransmembrane helix

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