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TIMM10 antibody

CAT: 0710-FNab08695Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08695Size:100 µg
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Background
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Synonyms
Mitochondrial import inner membrane translocase subunit Tim10|TIMM10|TIM10
Gene ID
26519
UniProt
P62072
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Translocase of inner mitochondrial membrane 10 homolog (yeast)
Target
TIMM10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
10 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P62072

Mitochondrial import inner membrane translocase subunit Tim10

TIM10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P62072
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TIMM10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K136, Q9WV99, Q9WVA0, Q9Y5J8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Chaperone

PTM

Disulfide bond

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Ligand

Metal-bindingZinc

Biological process

Protein transportTranslocationTransport