TFEC antibody

• Background :

  Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) . Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity) . Collaborates with MITF in target gene activation (By similarity) . Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity) . Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity) . Binds DNA in a homo-or heterodimeric form.

• Synonyms :

  Transcription factor EC (TFE-C) |Class E basic helix-loop-helix protein 34 (bHLHe34) |Transcription factor EC-like (hTFEC-L) |TFEC|BHLHE34|TCFEC|TFECL

• Gene ID :

  22797

• UniProt :

  O14948

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Transcription factor EC

• Target :

  TFEC

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IP

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  65 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IP