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TFE3 antibody

CAT: 0710-FNab08626Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08626Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4 (+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Synonyms
Transcription factor E3|Class E basic helix-loop-helix protein 33 (bHLHe33) |TFE3|BHLHE33
Gene ID
7030
UniProt
P19532
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transcription factor binding to IGHM enhancer 3
Target
TFE3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP,IHC
Field of Research
Cancer, Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC
Immunogen Sequence
1-300aa

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