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TFEB antibody

CAT: 0710-FNab08627Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08627Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. The calcualted molecular weight of TFEB is 53 kDa, but modified TFEB is about 65-70 kDa.
Synonyms
Transcription factor EB|Class E basic helix-loop-helix protein 35 (bHLHe35) |TFEB|BHLHE35
Gene ID
7942
UniProt
P19484
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transcription factor EB
Target
TFEB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65-70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
43-200aa

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