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STIM2 antibody

CAT: 0710-FNab08322Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08322Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Functions as a highly sensitive Ca (2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca (2+) -influx. Regulates basal cytosolic and endoplasmic reticulum Ca (2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca (2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca (2+) release-activated Ca (2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca (2+) influx.
Synonyms
Stromal interaction molecule 2|STIM2|KIAA1482
Gene ID
57620
UniProt
Q9P246
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Stromal interaction molecule 2
Target
STIM2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP, WB
Field of Research
Neuroscience, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85-115 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IP, WB

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