Products for Research Use Only
RegisterLogin

STAT2 antibody

CAT: 0710-FNab08296Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab08296Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state (PubMed:9020188, PubMed:23391734) . Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively (PubMed:26122121) .
Synonyms
Signal transducer and activator of transcription 2|p113|STAT2
Gene ID
6773
UniProt
P52630
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Signal transducer and activator of transcription 2, 113kDa
Target
STAT2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Epigenetics, Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
113 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

Related Products

CatalogName
EM1378Mouse STAT2 (Signal Transducer And Activator Of Transcription 2) ELISA Kit
EH12654Human STAT2 (Signal transducer and activator of transcription 2) ELISA Kit
FNab08300STAT3 antibody
FNab08284STAM2 antibody
FNab08299STAT3 antibody
FNab08313STAU2 antibody
FNab08295STAT1 antibody
FNab08302STAT4 antibody
FNab08298STAT3 antibody
FNab08279STAC2 antibody

Alternative Products

CatalogName
GTR18186771STAT2 Antibody

Popular Products