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SNRPE antibody

CAT: 0710-FNab08076Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08076Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified.
Synonyms
Small nuclear ribonucleoprotein E (snRNP-E) |Sm protein E (Sm-E, SmE) |SNRPE
Gene ID
6635
UniProt
P62304
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Small nuclear ribonucleoprotein polypeptide E
Target
SNRPE
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
11 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF

UniProtKB · P62304

Small nuclear ribonucleoprotein E

RUXE_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P62304
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SNRPE
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
snRNP-E
EC number
—
Processing
—
Secondary accessions
B2R5B9, P08578, Q15498, Q5BKT2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmNucleusSpliceosome

Disease

Disease variantHypotrichosis

Biological process

mRNA processingmRNA splicing

Molecular function

RibonucleoproteinRNA-binding

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GTR17896697-01SNRPE Antibody

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